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COVIPEDIA
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Yuen, Kwok-Yung


Publications

Impact Factor

Cites


ReferenceImpact FactorCitesQuartile
Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, Liu L, Shan H, Lei CL, Hui DSC, Du B, Li LJ, Zeng G, Yuen KY, Chen RC, Tang CL, Wang T, Chen PY, Xiang J, Li SY, Wang JL, Liang ZJ, Peng YX, Wei L, Liu Y, Hu YH, Peng P, Wang JM, Liu JY, Chen Z, Li G, Zheng ZJ, Qiu SQ, Luo J, Ye CJ, Zhu SY, Zhong NS; China Medical Treatment Expert Group for Covid-19. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020 Apr 30;382(18):1708-1720. doi: 10.1056/NEJMoa2002032. Epub 2020 Feb 28. PubMed PMID: 32109013; PubMed Central PMCID: PMC7092819.
74.699
7454
1
Chan JF, Yuan S, Kok KH, To KK, Chu H, Yang J, Xing F, Liu J, Yip CC, Poon RW, Tsoi HW, Lo SK, Chan KH, Poon VK, Chan WM, Ip JD, Cai JP, Cheng VC, Chen H, Hui CK, Yuen KY. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet. 2020 Feb 15;395(10223):514-523. doi: 10.1016/S0140-6736(20)30154-9. Epub 2020 Jan 24. PubMed PMID: 31986261; PubMed Central PMCID: PMC7159286.
60.392
2620
1
To KK, Tsang OT, Leung WS, Tam AR, Wu TC, Lung DC, Yip CC, Cai JP, Chan JM, Chik TS, Lau DP, Choi CY, Chen LL, Chan WM, Chan KH, Ip JD, Ng AC, Poon RW, Luo CT, Cheng VC, Chan JF, Hung IF, Chen Z, Chen H, Yuen KY. Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study. Lancet Infect Dis. 2020 May;20(5):565-574. doi: 10.1016/S1473-3099(20)30196-1. Epub 2020 Mar 23. PubMed PMID: 32213337; PubMed Central PMCID: PMC7158907.
24.446
873
1
Chan JF, Kok KH, Zhu Z, Chu H, To KK, Yuan S, Yuen KY. Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan. Emerg Microbes Infect. 2020 Jan 28;9(1):221-236. doi: 10.1080/22221751.2020.1719902. eCollection 2020. Erratum in: Emerg Microbes Infect. 2020 Dec;9(1):540. PubMed PMID: 31987001; PubMed Central PMCID: PMC7067204.
6.212
753
Wang Q, Zhang Y, Wu L, Niu S, Song C, Zhang Z, Lu G, Qiao C, Hu Y, Yuen KY, Wang Q, Zhou H, Yan J, Qi J. Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2. Cell. 2020 May 14;181(4):894-904.e9. doi: 10.1016/j.cell.2020.03.045. Epub 2020 Apr 9. PubMed PMID: 32275855; PubMed Central PMCID: PMC7144619.
38.637
460
1
To KK, Tsang OT, Chik-Yan Yip C, Chan KH, Wu TC, Chan JMC, Leung WS, Chik TS, Choi CY, Kandamby DH, Lung DC, Tam AR, Poon RW, Fung AY, Hung IF, Cheng VC, Chan JF, Yuen KY. Consistent detection of 2019 novel coronavirus in saliva. Clin Infect Dis. 2020 Feb 12. pii: ciaa149. doi: 10.1093/cid/ciaa149. [Epub ahead of print] PubMed PMID: 32047895; PubMed Central PMCID: PMC7108139.
8.313
411
1
Hung IF, Lung KC, Tso EY, Liu R, Chung TW, Chu MY, Ng YY, Lo J, Chan J, Tam AR, Shum HP, Chan V, Wu AK, Sin KM, Leung WS, Law WL, Lung DC, Sin S, Yeung P, Yip CC, Zhang RR, Fung AY, Yan EY, Leung KH, Ip JD, Chu AW, Chan WM, Ng AC, Lee R, Fung K, Yeung A, Wu TC, Chan JW, Yan WW, Chan WM, Chan JF, Lie AK, Tsang OT, Cheng VC, Que TL, Lau CS, Chan KH, To KK, Yuen KY. Triple combination of interferon beta-1b, lopinavir-ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial. Lancet. 2020 May 8. pii: S0140-6736(20)31042-4. doi: 10.1016/S0140-6736(20)31042-4. [Epub ahead of print] PubMed PMID: 32401715; PubMed Central PMCID: PMC7211500.
60.392
368
1
Chan JF, Yip CC, To KK, Tang TH, Wong SC, Leung KH, Fung AY, Ng AC, Zou Z, Tsoi HW, Choi GK, Tam AR, Cheng VC, Chan KH, Tsang OT, Yuen KY. Improved Molecular Diagnosis of COVID-19 by the Novel, Highly Sensitive and Specific COVID-19-RdRp/Hel Real-Time Reverse Transcription-PCR Assay Validated In Vitro and with Clinical Specimens. J Clin Microbiol. 2020 Apr 23;58(5). pii: e00310-20. doi: 10.1128/JCM.00310-20. Print 2020 Apr 23. PubMed PMID: 32132196; PubMed Central PMCID: PMC7180250.
5.897
267
1
Chan JF, Zhang AJ, Yuan S, Poon VK, Chan CC, Lee AC, Chan WM, Fan Z, Tsoi HW, Wen L, Liang R, Cao J, Chen Y, Tang K, Luo C, Cai JP, Kok KH, Chu H, Chan KH, Sridhar S, Chen Z, Chen H, To KK, Yuen KY. Simulation of the clinical and pathological manifestations of Coronavirus Disease 2019 (COVID-19) in golden Syrian hamster model: implications for disease pathogenesis and transmissibility. Clin Infect Dis. 2020 Mar 26. pii: ciaa325. doi: 10.1093/cid/ciaa325. [Epub ahead of print] PubMed PMID: 32215622; PubMed Central PMCID: PMC7184405.
8.313
183
1
Chu H, Chan JF, Wang Y, Yuen TT, Chai Y, Hou Y, Shuai H, Yang D, Hu B, Huang X, Zhang X, Cai JP, Zhou J, Yuan S, Kok KH, To KK, Chan IH, Zhang AJ, Sit KY, Au WK, Yuen KY. Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19. Clin Infect Dis. 2020 Apr 9. pii: ciaa410. doi: 10.1093/cid/ciaa410. [Epub ahead of print] PubMed PMID: 32270184; PubMed Central PMCID: PMC7184390.
8.313
164
1
Cheng VCC, Wong SC, Chen JHK, Yip CCY, Chuang VWM, Tsang OTY, Sridhar S, Chan JFW, Ho PL, Yuen KY. Escalating infection control response to the rapidly evolving epidemiology of the coronavirus disease 2019 (COVID-19) due to SARS-CoV-2 in Hong Kong. Infect Control Hosp Epidemiol. 2020 May;41(5):493-498. doi: 10.1017/ice.2020.58. Epub 2020 Mar 5. PubMed PMID: 32131908; PubMed Central PMCID: PMC7137535.
2.938
143
2
Cheng VC, Wong SC, Chan VW, So SY, Chen JH, Yip CC, Chan KH, Chu H, Chung TW, Sridhar S, To KK, Chan JF, Hung IF, Ho PL, Yuen KY. Air and environmental sampling for SARS-CoV-2 around hospitalized patients with coronavirus disease 2019 (COVID-19). Infect Control Hosp Epidemiol. 2020 Jun 8:1-32. doi: 10.1017/ice.2020.282. [Epub ahead of print] PubMed PMID: 32507114.
2.938
143
2
Cheng VC, Wong SC, Chuang VW, So SY, Chen JH, Sridhar S, To KK, Chan JF, Hung IF, Ho PL, Yuen KY. The role of community-wide wearing of face mask for control of coronavirus disease 2019 (COVID-19) epidemic due to SARS-CoV-2. J Infect. 2020 Apr 23. pii: S0163-4453(20)30235-8. doi: 10.1016/j.jinf.2020.04.024. [Epub ahead of print] PubMed PMID: 32335167; PubMed Central PMCID: PMC7177146.
4.842
112
1
Liu L, Wang P, Nair MS, Yu J, Rapp M, Wang Q, Luo Y, Chan JF, Sahi V, Figueroa A, Guo XV, Cerutti G, Bimela J, Gorman J, Zhou T, Chen Z, Yuen KY, Kwong PD, Sodroski JG, Yin MT, Sheng Z, Huang Y, Shapiro L, Ho DD. Potent neutralizing antibodies directed to multiple epitopes on SARS-CoV-2 spike. Nature. 2020 Jul 22. doi: 10.1038/s41586-020-2571-7. [Epub ahead of print] PubMed PMID: 32698192.
42.778
111
1
Chu H, Chan JF, Yuen TT, Shuai H, Yuan S, Wang Y, Hu B, Yip CC, Tsang JO, Huang X, Chai Y, Yang D, Hou Y, Chik KK, Zhang X, Fung AY, Tsoi HW, Cai JP, Chan WM, Ip JD, Chu AW, Zhou J, Lung DC, Kok KH, To KK, Tsang OT, Chan KH, Yuen KY. Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory studies of COVID-19: an observational study. Lancet Microbe. 2020 May;1(1):e14-e23. doi: 10.1016/S2666-5247(20)30004-5. Epub 2020 Apr 21. PubMed PMID: 32835326; PubMed Central PMCID: PMC7173822.
99
Wu Y, Ho W, Huang Y, Jin DY, Li S, Liu SL, Liu X, Qiu J, Sang Y, Wang Q, Yuen KY, Zheng ZM. SARS-CoV-2 is an appropriate name for the new coronavirus. Lancet. 2020 Mar 21;395(10228):949-950. doi: 10.1016/S0140-6736(20)30557-2. Epub 2020 Mar 6. PubMed PMID: 32151324; PubMed Central PMCID: PMC7133598.
60.392
78
1
Riva L, Yuan S, Yin X, Martin-Sancho L, Matsunaga N, Pache L, Burgstaller-Muehlbacher S, De Jesus PD, Teriete P, Hull MV, Chang MW, Chan JF, Cao J, Poon VK, Herbert KM, Cheng K, Nguyen TH, Rubanov A, Pu Y, Nguyen C, Choi A, Rathnasinghe R, Schotsaert M, Miorin L, Dejosez M, Zwaka TP, Sit KY, Martinez-Sobrido L, Liu WC, White KM, Chapman ME, Lendy EK, Glynne RJ, Albrecht R, Ruppin E, Mesecar AD, Johnson JR, Benner C, Sun R, Schultz PG, Su AI, García-Sastre A, Chatterjee AK, Yuen KY, Chanda SK. Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing. Nature. 2020 Jul 24. doi: 10.1038/s41586-020-2577-1. [Epub ahead of print] PubMed PMID: 32707573.
42.778
57
1
Lau SY, Wang P, Mok BW, Zhang AJ, Chu H, Lee AC, Deng S, Chen P, Chan KH, Song W, Chen Z, To KK, Chan JF, Yuen KY, Chen H. Attenuated SARS-CoV-2 variants with deletions at the S1/S2 junction. Emerg Microbes Infect. 2020 Dec;9(1):837-842. doi: 10.1080/22221751.2020.1756700. PubMed PMID: 32301390.
6.212
52
Yuen CK, Lam JY, Wong WM, Mak LF, Wang X, Chu H, Cai JP, Jin DY, To KK, Chan JF, Yuen KY, Kok KH. SARS-CoV-2 nsp13, nsp14, nsp15 and orf6 function as potent interferon antagonists. Emerg Microbes Infect. 2020 Dec;9(1):1418-1428. doi: 10.1080/22221751.2020.1780953. PubMed PMID: 32529952.
6.212
39
Zhou R, To KK, Wong YC, Liu L, Zhou B, Li X, Huang H, Mo Y, Luk TY, Lau TT, Yeung P, Chan WM, Wu AK, Lung KC, Tsang OT, Leung WS, Hung IF, Yuen KY, Chen Z. Acute SARS-CoV-2 Infection Impairs Dendritic Cell and T Cell Responses. Immunity. 2020 Aug 4. pii: S1074-7613(20)30333-2. doi: 10.1016/j.immuni.2020.07.026. [Epub ahead of print] PubMed PMID: 32791036.
22.553
34
1
Chan JF, Yuan S, Zhang AJ, Poon VK, Chan CC, Lee AC, Fan Z, Li C, Liang R, Cao J, Tang K, Luo C, Cheng VC, Cai JP, Chu H, Chan KH, To KK, Sridhar S, Yuen KY. Surgical mask partition reduces the risk of non-contact transmission in a golden Syrian hamster model for Coronavirus Disease 2019 (COVID-19). Clin Infect Dis. 2020 May 30. pii: ciaa644. doi: 10.1093/cid/ciaa644. [Epub ahead of print] PubMed PMID: 32472679.
8.313
34
1
Yip CC, Ho CC, Chan JF, To KK, Chan HS, Wong SC, Leung KH, Fung AY, Ng AC, Zou Z, Tam AR, Chung TW, Chan KH, Hung IF, Cheng VC, Tsang OT, Tsui SKW, Yuen KY. Development of a Novel, Genome Subtraction-Derived, SARS-CoV-2-Specific COVID-19-nsp2 Real-Time RT-PCR Assay and Its Evaluation Using Clinical Specimens. Int J Mol Sci. 2020 Apr 8;21(7). pii: E2574. doi: 10.3390/ijms21072574. PubMed PMID: 32276333; PubMed Central PMCID: PMC7177594.
4.556
29
1
Zhang BZ, Chu H, Han S, Shuai H, Deng J, Hu YF, Gong HR, Lee AC, Zou Z, Yau T, Wu W, Hung IF, Chan JF, Yuen KY, Huang JD. SARS-CoV-2 infects human neural progenitor cells and brain organoids. Cell Res. 2020 Aug 4. doi: 10.1038/s41422-020-0390-x. [Epub ahead of print] PubMed PMID: 32753756.
20.507
23
1
Chen JH, Yip CC, Poon RW, Chan KH, Cheng VC, Hung IF, Chan JF, Yuen KY, To KK. Evaluating the use of posterior oropharyngeal saliva in a point-of-care assay for the detection of SARS-CoV-2. Emerg Microbes Infect. 2020 May 27:1-14. doi: 10.1080/22221751.2020.1775133. [Epub ahead of print] PubMed PMID: 32459137.
6.212
23
Chan KH, Sridhar S, Zhang RR, Chu H, Fung AY, Chan G, Chan JF, To KK, Hung IF, Cheng VC, Yuen KY. Factors affecting stability and infectivity of SARS-CoV-2. J Hosp Infect. 2020 Jul 8. pii: S0195-6701(20)30339-X. doi: 10.1016/j.jhin.2020.07.009. [Epub ahead of print] PubMed PMID: 32652214.
3.271
23
1
To KK, Cheng VC, Cai JP, Chan KH, Chen LL, Wong LH, Choi CY, Fong CH, Ng AC, Lu L, Luo CT, Situ J, Chung TW, Wong SC, Kwan GS, Sridhar S, Chan JF, Fan CY, Chuang VWM, Kok KH, Hung IF, Yuen KY. Seroprevalence of SARS-CoV-2 in Hong Kong and in residents evacuated from Hubei province, China: a multicohort study. Lancet Microbe. 2020 Jul;1(3):e111-e118. doi: 10.1016/S2666-5247(20)30053-7. Epub 2020 Jun 3. PubMed PMID: 33230504; PubMed Central PMCID: PMC7673299.
23
Yang D, Chu H, Hou Y, Chai Y, Shuai H, Lee AC, Zhang X, Wang Y, Hu B, Huang X, Yuen TT, Cai JP, Zhou J, Yuan S, Zhang AJ, Chan JF, Yuen KY. Attenuated interferon and pro-inflammatory response in SARS-CoV-2-infected human dendritic cells is associated with viral antagonism of STAT1 phosphorylation. J Infect Dis. 2020 Jun 21. pii: jiaa356. doi: 10.1093/infdis/jiaa356. [Epub ahead of print] PubMed PMID: 32563187.
5.022
17
1
Hung IF, Cheng VC, Li X, Tam AR, Hung DL, Chiu KH, Yip CC, Cai JP, Ho DT, Wong SC, Leung SS, Chu MY, Tang MO, Chen JH, Poon RW, Fung AY, Zhang RR, Yan EY, Chen LL, Choi CY, Leung KH, Chung TW, Lam SH, Lam TP, Chan JF, Chan KH, Wu TC, Ho PL, Chan JW, Lau CS, To KK, Yuen KY. SARS-CoV-2 shedding and seroconversion among passengers quarantined after disembarking a cruise ship: a case series. Lancet Infect Dis. 2020 Jun 12. pii: S1473-3099(20)30364-9. doi: 10.1016/S1473-3099(20)30364-9. [Epub ahead of print] PubMed PMID: 32539986; PubMed Central PMCID: PMC7292581.
24.446
16
1
Chan KH, Yuen KY. COVID-19 epidemic: disentangling the re-emerging controversy about medical facemasks from an epidemiological perspective. Int J Epidemiol. 2020 Mar 31. pii: dyaa044. doi: 10.1093/ije/dyaa044. [Epub ahead of print] PubMed PMID: 32232402; PubMed Central PMCID: PMC7184463.
7.707
14
1
Liu L, To KK, Chan KH, Wong YC, Zhou R, Kwan KY, Fong CH, Chen LL, Choi CY, Lu L, Tsang OT, Leung WS, To WK, Hung IF, Yuen KY, Chen Z. High neutralizing antibody titer in intensive care unit patients with COVID-19. Emerg Microbes Infect. 2020 Jul 3:1-30. doi: 10.1080/22221751.2020.1791738. [Epub ahead of print] PubMed PMID: 32618497.
6.212
14
Cheng VC, Wong SC, Yuen KY. Estimating Coronavirus Disease 2019 Infection Risk in Health Care Workers. JAMA Netw Open. 2020 May 1;3(5):e209687. doi: 10.1001/jamanetworkopen.2020.9687. PubMed PMID: 32437571.
5.032
11
1
Yuan S, Chan CC, Chik KK, Tsang JO, Liang R, Cao J, Tang K, Cai JP, Ye ZW, Yin F, To KK, Chu H, Jin DY, Hung IF, Yuen KY, Chan JF. Broad-Spectrum Host-Based Antivirals Targeting the Interferon and Lipogenesis Pathways as Potential Treatment Options for the Pandemic Coronavirus Disease 2019 (COVID-19). Viruses. 2020 Jun 10;12(6). pii: E628. doi: 10.3390/v12060628. PubMed PMID: 32532085.
3.811
11
Zhang X, Chu H, Wen L, Shuai H, Yang D, Wang Y, Hou Y, Zhu Z, Yuan S, Yin F, Chan JF, Yuen KY. Competing endogenous RNA network profiling reveals novel host dependency factors required for MERS-CoV propagation. Emerg Microbes Infect. 2020 Dec;9(1):733-746. doi: 10.1080/22221751.2020.1738277. PubMed PMID: 32223537; PubMed Central PMCID: PMC7170352.
11
Yuan S, Chan JFW, Chik KKH, Chan CCY, Tsang JOL, Liang R, Cao J, Tang K, Chen LL, Wen K, Cai JP, Ye ZW, Lu G, Chu H, Jin DY, Yuen KY. Discovery of the FDA-approved drugs bexarotene, cetilistat, diiodohydroxyquinoline, and abiraterone as potential COVID-19 treatments with a robust two-tier screening system. Pharmacol Res. 2020 May 27:104960. doi: 10.1016/j.phrs.2020.104960. [Epub ahead of print] PubMed PMID: 32473310; PubMed Central PMCID: PMC7254006.
5.893
10
1
Yip CC, Sridhar S, Cheng AK, Leung KH, Choi GK, Chen JH, Poon RW, Chan KH, Wu AK, Chan HS, Chau SK, Chung TW, To KK, Tsang OT, Hung IF, Cheng VC, Yuen KY, Chan JF. Evaluation of the commercially available LightMix® Modular E-gene kit using clinical and proficiency testing specimens for SARS-CoV-2 detection. J Clin Virol. 2020 May 27;129:104476. doi: 10.1016/j.jcv.2020.104476. [Epub ahead of print] PubMed PMID: 32516739; PubMed Central PMCID: PMC7255195.
2.777
10
3
Chung TW, Sridhar S, Zhang AJ, Chan KH, Li HL, Wong FK, Ng MY, Tsang RK, Lee AC, Fan Z, Ho RS, Luk SY, Kan WK, Lam SH, Wu AK, Leung SM, Chan WM, Ng PY, To KK, Cheng VC, Lung KC, Hung IF, Yuen KY. Olfactory Dysfunction in Coronavirus Disease 2019 Patients: Observational Cohort Study and Systematic Review. Open Forum Infect Dis. 2020 Jun 5;7(6):ofaa199. doi: 10.1093/ofid/ofaa199. eCollection 2020 Jun. PubMed PMID: 32548209; PubMed Central PMCID: PMC7284010.
3.656
9
2
Yuan S, Wang R, Chan JF, Zhang AJ, Cheng T, Chik KK, Ye ZW, Wang S, Lee AC, Jin L, Li H, Jin DY, Yuen KY, Sun H. Metallodrug ranitidine bismuth citrate suppresses SARS-CoV-2 replication and relieves virus-associated pneumonia in Syrian hamsters. Nat Microbiol. 2020 Oct 7. doi: 10.1038/s41564-020-00802-x. [Epub ahead of print] PubMed PMID: 33028965.
15.54
8
1
Hung DL, Li X, Chiu KH, Yip CC, To KK, Chan JF, Sridhar S, Chung TW, Lung KC, Liu RW, Kwan GS, Hung IF, Cheng VC, Yuen KY. Early-Morning vs Spot Posterior Oropharyngeal Saliva for Diagnosis of SARS-CoV-2 Infection: Implication of Timing of Specimen Collection for Community-Wide Screening. Open Forum Infect Dis. 2020 Jun 7;7(6):ofaa210. doi: 10.1093/ofid/ofaa210. eCollection 2020 Jun. PubMed PMID: 32577428; PubMed Central PMCID: PMC7299521.
3.656
5
2
Li X, Chan JF, Li KK, Tso EY, Yip CC, Sridhar S, Chung TW, Chiu KH, Hung DL, Wu AK, Chau SK, Liu R, Lung KC, Tam AR, Cheng VC, To KK, Chan KH, Hung IF, Yuen KY. Detection of SARS-CoV-2 in conjunctival secretions from patients without ocular symptoms. Infection. 2020 Sep 17. doi: 10.1007/s15010-020-01524-2. [Epub ahead of print] PubMed PMID: 32944840.
3.04
5
2
Shuai H, Chu H, Hou Y, Yang D, Wang Y, Hu B, Huang X, Zhang X, Chai Y, Cai JP, Chan JF, Yuen KY. Differential immune activation profile of SARS-CoV-2 and SARS-CoV infection in human lung and intestinal cells: implications for treatment with IFN-β and IFN inducer. J Infect. 2020 Jul 21. pii: S0163-4453(20)30490-4. doi: 10.1016/j.jinf.2020.07.016. [Epub ahead of print] PubMed PMID: 32707230.
4.842
4
1
Lau SKP, Li KSM, Luk HKH, He Z, Teng JLL, Yuen KY, Wernery U, Woo PCY. Middle East Respiratory Syndrome Coronavirus Antibodies in Bactrian and Hybrid Camels from Dubai. mSphere. 2020 Jan 22;5(1). pii: e00898-19. doi: 10.1128/mSphere.00898-19. PubMed PMID: 31969478; PubMed Central PMCID: PMC6977179.
4.282
4
1
Chu AW, Chan WM, Ip JD, Yip CC, Chan JF, Yuen KY, To KK. Evaluation of simple nucleic acid extraction methods for the detection of SARS-CoV-2 in nasopharyngeal and saliva specimens during global shortage of extraction kits. J Clin Virol. 2020 Jun 23;129:104519. doi: 10.1016/j.jcv.2020.104519. [Epub ahead of print] PubMed PMID: 32629187; PubMed Central PMCID: PMC7309780.
2.777
4
3
Chan WM, Ip JD, Chu AW, Yip CC, Lo LS, Chan KH, Ng AC, Poon RW, To WK, Tsang OT, Leung WS, Kwan MY, Chua GT, Chung TW, Hung IF, Kok KH, Cheng VC, Chan JF, Yuen KY, To KK. Identification of nsp1 gene as the target of SARS-CoV-2 real-time RT-PCR using nanopore whole genome sequencing. J Med Virol. 2020 Jun 5. doi: 10.1002/jmv.26140. [Epub ahead of print] PubMed PMID: 32501535.
2.021
4
4
Thompson S, Bohn MK, Mancini N, Loh TP, Wang CB, Grimmler M, Yuen KY, Mueller R, Koch D, Sethi S, Rawlinson WD, Clementi M, Erasmus R, Leportier M, Kwon GC, Menezes ME, Patru MM, Gramegna M, Singh K, Najjar O, Ferrari M, Lippi G, Adeli K, Horvath A. IFCC interim guidelines on biochemical/hematological monitoring of COVID-19 patients. Clin Chem Lab Med. 2020 Oct 7. pii: /j/cclm.ahead-of-print/cclm-2020-1414/cclm-2020-1414.xml. doi: 10.1515/cclm-2020-1414. [Epub ahead of print] PubMed PMID: 33027044.
3.595
3
1
Bohn MK, Mancini N, Loh TP, Wang CB, Grimmler M, Gramegna M, Yuen KY, Mueller R, Koch D, Sethi S, Rawlinson WD, Clementi M, Erasmus R, Leportier M, Kwon GC, Menezes ME, Patru MM, Singh K, Ferrari M, Najjar O, Horvath A, Adeli K, Lippi G. IFCC interim guidelines on molecular testing of SARS-CoV-2 infection. Clin Chem Lab Med. 2020 Oct 7. pii: /j/cclm.ahead-of-print/cclm-2020-1412/cclm-2020-1412.xml. doi: 10.1515/cclm-2020-1412. [Epub ahead of print] PubMed PMID: 33027042.
3.595
3
1
Cheng VCC, Wong SC, Chuang VWM, So SYC, Chen JHK, Sridhar S, To KKW, Chan JFW, Hung IFN, Ho PL, Yuen KY. Absence of nosocomial transmission of coronavirus disease 2019 (COVID-19) due to SARS-CoV-2 in the pre-pandemic phase in Hong Kong. Am J Infect Control. 2020 May 24. pii: S0196-6553(20)30280-7. doi: 10.1016/j.ajic.2020.05.018. [Epub ahead of print] PubMed PMID: 32461068.
2.294
3
2
Yuan S, Chu H, Huang J, Zhao X, Ye ZW, Lai PM, Wen L, Cai JP, Mo Y, Cao J, Liang R, Poon VK, Sze KH, Zhou J, To KK, Chen Z, Chen H, Jin DY, Chan JF, Yuen KY. Viruses harness YxxØ motif to interact with host AP2M1 for replication: A vulnerable broad-spectrum antiviral target. Sci Adv. 2020 Aug 28;6(35):eaba7910. doi: 10.1126/sciadv.aba7910. eCollection 2020 Aug. PubMed PMID: 32923629; PubMed Central PMCID: PMC7455044.
13.116
2
1
Zhao H, To KKW, Sze KH, Yung TT, Bian M, Lam H, Yeung ML, Li C, Chu H, Yuen KY. A broad-spectrum virus- and host-targeting peptide against respiratory viruses including influenza virus and SARS-CoV-2. Nat Commun. 2020 Aug 25;11(1):4252. doi: 10.1038/s41467-020-17986-9. PubMed PMID: 32843628.
12.121
2
1
Chen JH, Yip CC, Chan JF, Poon RW, To KK, Chan KH, Cheng VC, Yuen KY. Clinical performance of the Luminex NxTAG CoV Extended Panel for SARS-CoV-2 detection in nasopharyngeal specimens of COVID-19 patients in Hong Kong. J Clin Microbiol. 2020 Jun 1. pii: JCM.00936-20. doi: 10.1128/JCM.00936-20. [Epub ahead of print] PubMed PMID: 32482633.
5.897
2
1
Chan JF, To KK, Yuen KY. A case series of children with Coronavirus Disease 2019: what have we learned? Clin Infect Dis. 2020 Apr 22. pii: ciaa469. doi: 10.1093/cid/ciaa469. [Epub ahead of print] PubMed PMID: 32318718; PubMed Central PMCID: PMC7188164.
8.313
1
1
Chan KH, Yuen KY. Erratum to: COVID-19 epidemic: disentangling the re-emerging controversy about medical facemasks from an epidemiological perspective. Int J Epidemiol. 2020 Nov 5. pii: dyaa189. doi: 10.1093/ije/dyaa189. [Epub ahead of print] PubMed PMID: 33147615.
7.707
1
1
Fong CH, Cai JP, Dissanayake TK, Chen LL, Choi CY, Wong LH, Ng AC, Pang PKP, Ho DT, Poon RW, Chung TW, Sridhar S, Chan KH, Chan JF, Hung IF, Yuen KY, To KK. Improved Detection of Antibodies against SARS-CoV-2 by Microsphere-Based Antibody Assay. Int J Mol Sci. 2020 Sep 9;21(18). pii: E6595. doi: 10.3390/ijms21186595. PubMed PMID: 32916926.
4.556
1
1
Yip CC, Sridhar S, Leung KH, Ng AC, Chan KH, Chan JF, Tsang OT, Hung IF, Cheng VC, Yuen KY, To KK. Development and Evaluation of Novel and Highly Sensitive Single-Tube Nested Real-Time RT-PCR Assays for SARS-CoV-2 Detection. Int J Mol Sci. 2020 Aug 7;21(16). pii: E5674. doi: 10.3390/ijms21165674. PubMed PMID: 32784770.
4.556
1
1
Yee Lim C, Kathryn Bohn M, Lippi G, Ferrari M, Ping Loh T, Yuen KY, Adeli K, Rita Horvath A; IFCC Task Force on COVID-19. Staff rostering, split team arrangement, social distancing (physical distancing) and use of personal protective equipment to minimize risk of workplace transmission during the COVID-19 pandemic: a simulation study. Clin Biochem. 2020 Sep 11. pii: S0009-9120(20)30839-0. doi: 10.1016/j.clinbiochem.2020.09.003. [Epub ahead of print] PubMed PMID: 32926883.
2.573
1
2
Yuen CK, Wong WM, Mak LF, Wang X, Chu H, Yuen KY, Kok KH. Suppression of SARS-CoV-2 infection in ex-vivo human lung tissues by targeting class III phosphoinositide 3-kinase. J Med Virol. 2020 Oct 7. doi: 10.1002/jmv.26583. [Epub ahead of print] PubMed PMID: 33026649.
2.021
1
4
Hung IF, Yuen KY. Early triple antiviral therapy for COVID-19 - Authors' reply. Lancet. 2020 Nov 7;396(10261):1488. doi: 10.1016/S0140-6736(20)32268-6. PubMed PMID: 33160568.
60.392
0
Chu H, Fuk-Woo Chan J, Wang Y, Tsz-Tai Yuen T, Chai Y, Shuai H, Yang D, Hu B, Huang X, Zhang X, Hou Y, Cai JP, Zhang AJ, Zhou J, Yuan S, Kai-Wang To K, Fan-Ngai Hung I, Cheung TT, Tsui-Lin Ng A, Hau-Yee Chan I, Yu-Hong Wong I, Ying-Kit Law S, Chi-Chung Foo D, Leung WK, Yuen KY. SARS-CoV-2 induces a more robust innate immune response and replicates less efficiently than SARS-CoV in the human intestines: an ex vivo study with implications on pathogenesis of COVID-19. Cell Mol Gastroenterol Hepatol. 2020 Sep 30. pii: S2352-345X(20)30160-0. doi: 10.1016/j.jcmgh.2020.09.017. [Epub ahead of print] PubMed PMID: 33010495.
7.076
0
1
Wang X, Lam JY, Wong WM, Yuen CK, Cai JP, Au SW, Chan JF, To KKW, Kok KH, Yuen KY. Accurate Diagnosis of COVID-19 by a Novel Immunogenic Secreted SARS-CoV-2 orf8 Protein. mBio. 2020 Oct 20;11(5). pii: e02431-20. doi: 10.1128/mBio.02431-20. PubMed PMID: 33082264.
6.784
0
1
Ye ZW, Yuan S, Chan JF, Zhang AJ, Yu CY, Ong CP, Yang D, Chan CC, Tang K, Cao J, Poon VK, Chan CC, Cai JP, Chu H, Yuen KY, Jin DY. Beneficial effect of combinational methylprednisolone and remdesivir in hamster model of SARS-CoV-2 infection. Emerg Microbes Infect. 2021 Feb 4:1-38. doi: 10.1080/22221751.2021.1885998. [Epub ahead of print] PubMed PMID: 33538646.
5.776
0
Wong LR, Ye ZW, Lui PY, Zheng X, Yuan S, Zhu L, Fung SY, Yuen KS, Siu KL, Yeung ML, Cai Z, Woo PC, Yuen KY, Chan CP, Jin DY. Middle East Respiratory Syndrome Coronavirus ORF8b Accessory Protein Suppresses Type I IFN Expression by Impeding HSP70-Dependent Activation of IRF3 Kinase IKKε. J Immunol. 2020 Aug 3. pii: ji1901489. doi: 10.4049/jimmunol.1901489. [Epub ahead of print] PubMed PMID: 32747502.
4.886
0
2
Wong SC, Lam GK, AuYeung CH, Chan VW, Wong NL, So SY, Chen JH, Hung IF, Chan JF, Yuen KY, Cheng VC. Absence of nosocomial influenza and respiratory syncytial virus infection in the coronavirus disease 2019 (COVID-19) era: implication of universal masking in hospitals. Infect Control Hosp Epidemiol. 2020 Aug 17:1-14. doi: 10.1017/ice.2020.425. [Epub ahead of print] PubMed PMID: 32799965.
2.938
0
2
Lam JY, Yuen CK, Ip JD, Wong WM, To KK, Yuen KY, Kok KH. Loss of orf3b in the circulating SARS-CoV-2 strains. Emerg Microbes Infect. 2020 Nov 18:1-678. doi: 10.1080/22221751.2020.1852892. [Epub ahead of print] PubMed PMID: 33205709.
0
To KK, Yuen KY. Seroprevalence of SARS-CoV-2 in Hong Kong returnees - Authors' reply. Lancet Microbe. 2020 Aug;1(4):e148. doi: 10.1016/S2666-5247(20)30092-6. Epub 2020 Aug 6. PubMed PMID: 33521714; PubMed Central PMCID: PMC7834862.
0
Lu L, Fong CH, Zhang AJ, Wu WL, Li IC, Lee AC, Dissanayake TK, Chen L, Hung IF, Chan KH, Chu H, Kok KH, Yuen KY, To KK. Repurposing of Miltefosine as an Adjuvant for Influenza Vaccine. Vaccines (Basel). 2020 Dec 11;8(4). pii: E754. doi: 10.3390/vaccines8040754. PubMed PMID: 33322574.
0
Yuan S, Yin X, Meng X, Chan JF, Ye ZW, Riva L, Pache L, Chan CC, Lai PM, Chan CC, Poon VK, Lee AC, Matsunaga N, Pu Y, Yuen CK, Cao J, Liang R, Tang K, Sheng L, Du Y, Xu W, Lau CY, Sit KY, Au WK, Wang R, Zhang YY, Tang YD, Clausen TM, Pihl J, Oh J, Sze KH, Zhang AJ, Chu H, Kok KH, Wang D, Cai XH, Esko JD, Hung IF, Li RA, Chen H, Sun H, Jin DY, Sun R, Chanda SK, Yuen KY. Clofazimine broadly inhibits coronaviruses including SARS-CoV-2. Nature. 2021 Mar 16. doi: 10.1038/s41586-021-03431-4. [Epub ahead of print] PubMed PMID: 33727703.
42.779
Yeung ML, Teng JLL, Jia L, Zhang C, Huang C, Cai JP, Zhou R, Chan KH, Zhao H, Zhu L, Siu KL, Fung SY, Yung S, Chan TM, To KK, Chan JF, Cai Z, Lau SKP, Chen Z, Jin DY, Woo PCY, Yuen KY. Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system. Cell. 2021 Mar 2. pii: S0092-8674(21)00283-X. doi: 10.1016/j.cell.2021.02.053. [Epub ahead of print] PubMed PMID: 33713620.
38.637
Zhou D, Chan JF, Zhou B, Zhou R, Li S, Shan S, Liu L, Zhang AJ, Chen SJ, Chan CC, Xu H, Poon VK, Yuan S, Li C, Chik KK, Chan CC, Cao J, Chan CY, Kwan KY, Du Z, Lau TT, Zhang Q, Zhou J, To KK, Zhang L, Ho DD, Yuen KY, Chen Z. Robust SARS-CoV-2 infection in nasal turbinates after treatment with systemic neutralizing antibodies. Cell Host Microbe. 2021 Feb 25. pii: S1931-3128(21)00098-6. doi: 10.1016/j.chom.2021.02.019. [Epub ahead of print] PubMed PMID: 33657424.
15.923
Chu H, Shuai H, Hou Y, Zhang X, Wen L, Huang X, Hu B, Yang D, Wang Y, Yoon C, Wong BH, Li C, Zhao X, Poon VK, Cai JP, Wong KK, Yeung ML, Zhou J, Au-Yeung RK, Yuan S, Jin DY, Kok KH, Perlman S, Chan JF, Yuen KY. Targeting highly pathogenic coronavirus-induced apoptosis reduces viral pathogenesis and disease severity. Sci Adv. 2021 Jun 16;7(25). pii: eabf8577. doi: 10.1126/sciadv.abf8577. Print 2021 Jun. PubMed PMID: 34134991.
13.117
Zhao H, To KKW, Lam H, Zhou X, Chan JF, Peng Z, Lee ACY, Cai J, Chan WM, Ip JD, Chan CC, Yeung ML, Zhang AJ, Chu AWH, Jiang S, Yuen KY. Cross-linking peptide and repurposed drugs inhibit both entry pathways of SARS-CoV-2. Nat Commun. 2021 Mar 9;12(1):1517. doi: 10.1038/s41467-021-21825-w. PubMed PMID: 33750821.
12.121
Chu H, Hu B, Huang X, Chai Y, Zhou D, Wang Y, Shuai H, Yang D, Hou Y, Zhang X, Yuen TT, Cai JP, Zhang AJ, Zhou J, Yuan S, To KK, Chan IH, Sit KY, Foo DC, Wong IY, Ng AT, Cheung TT, Law SY, Au WK, Brindley MA, Chen Z, Kok KH, Chan JF, Yuen KY. Host and viral determinants for efficient SARS-CoV-2 infection of the human lung. Nat Commun. 2021 Jan 8;12(1):134. doi: 10.1038/s41467-020-20457-w. PubMed PMID: 33420022.
12.121
Lau SKP, Fan RYY, Zhu L, Li KSM, Wong ACP, Luk HKH, Wong EYM, Lam CSF, Lo GCS, Fung J, He Z, Fok FCH, Au-Yeung RKH, Zhang L, Kok KH, Yuen KY, Woo PCY. Isolation of MERS-related coronavirus from lesser bamboo bats that uses DPP4 and infects human-DPP4-transgenic mice. Nat Commun. 2021 Jan 11;12(1):216. doi: 10.1038/s41467-020-20458-9. PubMed PMID: 33431849.
12.121
Wang P, Lau SY, Deng S, Chen P, Mok BW, Zhang AJ, Lee AC, Chan KH, Tam RC, Xu H, Zhou R, Song W, Liu L, To KK, Chan JF, Chen Z, Yuen KY, Chen H. Characterization of an attenuated SARS-CoV-2 variant with a deletion at the S1/S2 junction of the spike protein. Nat Commun. 2021 May 13;12(1):2790. doi: 10.1038/s41467-021-23166-0. PubMed PMID: 33986286.
12.121
Wang Q, Li Y, Lung DC, Chan PT, Dung CH, Jia W, Miao T, Huang J, Chen W, Wang Z, Leung KM, Lin Z, Wong D, Tse H, Wong SCY, Choi GK, Lam JY, To KK, Cheng VC, Yuen KY. Aerosol transmission of SARS-CoV-2 due to the chimney effect in two high-rise housing drainage stacks. J Hazard Mater. 2021 Aug 2;421:126799. doi: 10.1016/j.jhazmat.2021.126799. [Epub ahead of print] PubMed PMID: 34396958.
9.038
Chan JF, Poon VK, Chan CC, Chik KK, Tsang JO, Zou Z, Chan CC, Lee AC, Li C, Liang R, Cao J, Tang K, Yuen TT, Hu B, Huang X, Chai Y, Shuai H, Luo C, Cai JP, Chan KH, Sridhar S, Yin F, Kok KH, Chu H, Zhang AJ, Yuan S, Yuen KY. Low Environmental Temperature Exacerbates Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Golden Syrian Hamsters. Clin Infect Dis. 2021 Sep 18. pii: ciab817. doi: 10.1093/cid/ciab817. [Epub ahead of print] PubMed PMID: 34536277.
8.313
Chen LL, Lu L, Choi CY, Cai JP, Tsoi HW, Chu AW, Ip JD, Chan WM, Zhang RR, Zhang X, Tam AR, Lau DP, To WK, Que TL, Yip CC, Chan KH, Cheng VC, Yuen KY, Hung IF, To KK. Impact of SARS-CoV-2 variant-associated RBD mutations on the susceptibility to serum antibodies elicited by COVID-19 infection or vaccination. Clin Infect Dis. 2021 Jul 26. pii: ciab656. doi: 10.1093/cid/ciab656. [Epub ahead of print] PubMed PMID: 34309648.
8.313
Li C, Chen Y, Zhao Y, Lung DC, Ye Z, Song W, Liu FF, Cai JP, Wong WM, Yip CC, Chan JF, To KK, Sridhar S, Hung IF, Chu H, Kok KH, Jin DY, Zhang AJ, Yuen KY. Intravenous injection of COVID-19 mRNA vaccine can induce acute myopericarditis in mouse model. Clin Infect Dis. 2021 Aug 18. pii: ciab707. doi: 10.1093/cid/ciab707. [Epub ahead of print] PubMed PMID: 34406358.
8.313
To KK, Li X, Lung DC, Ip JD, Chan WM, Chu AW, Yip CC, Chen JHK, Poon RW, Tsoi HW, Lai RW, To WK, Ren L, Li M, Cao Y, Xie XS, Jin DY, Yuen KY. False COVID-19 cases due to contamination by inactivated virus vaccine. Clin Infect Dis. 2021 Sep 9. pii: ciab684. doi: 10.1093/cid/ciab684. [Epub ahead of print] PubMed PMID: 34498683.
8.313
Tse H, Lung DC, Wong SC, Ip KF, Wu TC, To KK, Kok KH, Yuen KY, Choi GK. Emergence of a Severe Acute Respiratory Syndrome Coronavirus 2 virus variant with novel genomic architecture in Hong Kong. Clin Infect Dis. 2021 Mar 2. pii: ciab198. doi: 10.1093/cid/ciab198. [Epub ahead of print] PubMed PMID: 33675655.
8.313
Li C, Chen YX, Liu FF, Lee AC, Zhao Y, Ye ZH, Cai JP, Chu H, Zhang RQ, Chan KH, Chiu KH, Lung DC, Sridhar S, Hung IF, To KK, Zhang AJ, Chan JF, Yuen KY. Absence of vaccine-enhanced disease with unexpected positive protection against SARS-CoV-2 by inactivated vaccine given within three days of virus challenge in Syrian hamster model. Clin Infect Dis. 2021 Jan 30. pii: ciab083. doi: 10.1093/cid/ciab083. [Epub ahead of print] PubMed PMID: 33515458.
8.313
Zhang AJ, Lee AC, Chan JF, Liu F, Li C, Chen Y, Chu H, Lau SY, Wang P, Chan CC, Poon VK, Yuan S, To KK, Chen H, Yuen KY. Co-infection by severe acute respiratory syndrome coronavirus 2 and influenza A(H1N1)pdm09 virus enhances the severity of pneumonia in golden Syrian hamsters. Clin Infect Dis. 2020 Nov 20. pii: ciaa1747. doi: 10.1093/cid/ciaa1747. [Epub ahead of print] PubMed PMID: 33216851.
8.313
To KK, Chan WM, Ip JD, Chu AW, Tam AR, Liu R, Wu AK, Lung KC, Tsang OT, Lau DP, To WK, Kwan MY, Yau YS, Ng AC, Yip CC, Chan KH, Tse H, Hung IF, Yuen KY. Unique SARS-CoV-2 clusters causing a large COVID-19 outbreak in Hong Kong. Clin Infect Dis. 2020 Aug 5. pii: ciaa1119. doi: 10.1093/cid/ciaa1119. [Epub ahead of print] PubMed PMID: 32756996.
8.313
1
Zhang AJ, Lee AC, Chu H, Chan JF, Fan Z, Li C, Liu F, Chen Y, Yuan S, Poon VK, Chan CC, Cai JP, Wu KL, Sridhar S, Chan YS, Yuen KY. SARS-CoV-2 infects and damages the mature and immature olfactory sensory neurons of hamsters. Clin Infect Dis. 2020 Jul 15. pii: ciaa995. doi: 10.1093/cid/ciaa995. [Epub ahead of print] PubMed PMID: 32667973.
8.313
1
To KK, Hung IF, Chan KH, Yuan S, To WK, Tsang DN, Cheng VC, Chen Z, Kok KH, Yuen KY. Serum antibody profile of a patient with COVID-19 reinfection. Clin Infect Dis. 2020 Sep 23. pii: ciaa1368. doi: 10.1093/cid/ciaa1368. [Epub ahead of print] PubMed PMID: 32966566.
8.313
1
To KK, Hung IF, Ip JD, Chu AW, Chan WM, Tam AR, Fong CH, Yuan S, Tsoi HW, Ng AC, Lee LL, Wan P, Tso E, To WK, Tsang D, Chan KH, Huang JD, Kok KH, Cheng VC, Yuen KY. COVID-19 re-infection by a phylogenetically distinct SARS-coronavirus-2 strain confirmed by whole genome sequencing. Clin Infect Dis. 2020 Aug 25. pii: ciaa1275. doi: 10.1093/cid/ciaa1275. [Epub ahead of print] PubMed PMID: 32840608.
8.313
1
Banach BB, Cerutti G, Fahad AS, Shen CH, Oliveira De Souza M, Katsamba PS, Tsybovsky Y, Wang P, Nair MS, Huang Y, Francino-Urdániz IM, Steiner PJ, Gutiérrez-González M, Liu L, López Acevedo SN, Nazzari AF, Wolfe JR, Luo Y, Olia AS, Teng IT, Yu J, Zhou T, Reddem ER, Bimela J, Pan X, Madan B, Laflin AD, Nimrania R, Yuen KY, Whitehead TA, Ho DD, Kwong PD, Shapiro L, DeKosky BJ. Paired heavy- and light-chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses. Cell Rep. 2021 Sep 28:109771. doi: 10.1016/j.celrep.2021.109771. [Epub ahead of print] PubMed PMID: 34587480.
8.109
Ip JD, Kok KH, Chan WM, Wing-Ho Chu A, Wu WL, Chik-Yan Yip C, To WK, Tak-Yin Tsang O, Leung WS, Shiu-Hong Chik T, Chan KH, Fan-Ngai Hung I, Yuen KY, Kai-Wang To K. Intrahost non-synonymous diversity at a neutralising antibody epitope of SARS-CoV-2 spike protein N-terminal domain. Clin Microbiol Infect. 2020 Oct 31. pii: S1198-743X(20)30661-3. doi: 10.1016/j.cmi.2020.10.030. [Epub ahead of print] PubMed PMID: 33144203; PubMed Central PMCID: PMC7605743.
7.117
1
Yuan S, Yin X, Meng X, Chan J, Ye ZW, Riva L, Pache L, Chan CC, Lai PM, Chan C, Poon V, Matsunaga N, Pu Y, Yuen CK, Cao J, Liang R, Tang K, Sheng L, Du Y, Xu W, Sze KH, Zhang J, Chu H, Kok KH, To K, Jin DY, Sun R, Chanda S, Yuen KY. Clofazimine is a broad-spectrum coronavirus inhibitor that antagonizes SARS-CoV-2 replication in primary human cell culture and hamsters. Res Sq. 2020 Oct 7. pii: rs.3.rs-86169. doi: 10.21203/rs.3.rs-86169/v1. PubMed PMID: 33052331; PubMed Central PMCID: PMC7553155.
6.763
Wang X, Lam JY, Chen L, Au SW, To KKW, Yuen KY, Kok KH. Mining of linear B cell epitopes of SARS-CoV-2 ORF8 protein from COVID-19 patients. Emerg Microbes Infect. 2021 May 18:1-19. doi: 10.1080/22221751.2021.1931465. [Epub ahead of print] PubMed PMID: 34003073.
5.776
To KK, Sridhar S, Chiu KH, Hung DL, Li X, Hung IF, Tam AR, Chung TW, Chan JF, Zhang AJ, Cheng VC, Yuen KY. Lessons learned one year after SARS-CoV-2 emergence leading to COVID-19 pandemic. Emerg Microbes Infect. 2021 Mar 5:1-89. doi: 10.1080/22221751.2021.1898291. [Epub ahead of print] PubMed PMID: 33666147.
5.776
Lu L, Chu AW, Zhang RR, Chan WM, Ip JD, Tsoi HW, Chen LL, Cai JP, Lung DC, Tam AR, Yau YS, Kwan MY, To WK, Tsang OT, Lee LL, Yi H, Ip TC, Poon RW, Siu GK, Mok BW, Cheng VC, Chan KH, Yuen KY, Hung IF, To KK. The impact of spike N501Y mutation on neutralizing activity and RBD binding of SARS-CoV-2 convalescent serum. EBioMedicine. 2021 Aug 19;71:103544. doi: 10.1016/j.ebiom.2021.103544. [Epub ahead of print] PubMed PMID: 34419925.
5.736
Wang J, Liang B, Chen Y, Fuk-Woo Chan J, Yuan S, Ye H, Nie L, Zhou J, Wu Y, Wu M, Huang LS, An J, Warshel A, Yuen KY, Ciechanover A, Huang Z, Xu Y. A new class of α-ketoamide derivatives with potent anticancer and anti-SARS-CoV-2 activities. Eur J Med Chem. 2021 Feb 10;215:113267. doi: 10.1016/j.ejmech.2021.113267. [Epub ahead of print] PubMed PMID: 33639344.
5.573
Wen L, Tang K, Chik KK, Chan CC, Tsang JO, Liang R, Cao J, Huang Y, Luo C, Cai JP, Ye ZW, Yin F, Chu H, Jin DY, Yuen KY, Yuan S, Chan JF. In silico structure-based discovery of a SARS-CoV-2 main protease inhibitor. Int J Biol Sci. 2021 Apr 10;17(6):1555-1564. doi: 10.7150/ijbs.59191. eCollection 2021. PubMed PMID: 33907519; PubMed Central PMCID: PMC8071767.
4.858
Martín-Sánchez M, Lim WW, Yeung A, Adam DC, Ali ST, Lau EHY, Wu P, Yuen KY, Leung GM, Cowling BJ. COVID-19 transmission in Hong Kong despite universal masking. J Infect. 2021 Apr 22. pii: S0163-4453(21)00205-X. doi: 10.1016/j.jinf.2021.04.019. [Epub ahead of print] PubMed PMID: 33895227.
4.842
Wong SC, Chen H, Lung DC, Ho PL, Yuen KY, Cheng VC. To prevent SARS-CoV-2 transmission in designated quarantine hotel for travelers: Is the ventilation system a concern? Indoor Air. 2021 Jul 14. doi: 10.1111/ina.12870. [Epub ahead of print] PubMed PMID: 34259364.
4.739
Lau SKP, Lung DC, Wong EYM, Aw-Yong KL, Wong ACP, Luk HKH, Li KSM, Fung J, Chan TTY, Tang JYM, Zhu L, Yip CCY, Wong SCY, Lee RA, Tsang OTY, Yuen KY, Woo PCY. Molecular Evolution of Human Coronavirus 229E in Hong Kong and a Fatal COVID-19 Case Involving Coinfection with a Novel Human Coronavirus 229E Genogroup. mSphere. 2021 Feb 10;6(1). pii: e00819-20. doi: 10.1128/mSphere.00819-20. PubMed PMID: 33568452.
4.282
Riva L, Yuan S, Yin X, Martin-Sancho L, Matsunaga N, Burgstaller-Muehlbacher S, Pache L, De Jesus PP, Hull MV, Chang M, Chan JF, Cao J, Poon VK, Herbert K, Nguyen TT, Pu Y, Nguyen C, Rubanov A, Martinez-Sobrido L, Liu WC, Miorin L, White KM, Johnson JR, Benner C, Sun R, Schultz PG, Su A, Garcia-Sastre A, Chatterjee AK, Yuen KY, Chanda SK. A Large-scale Drug Repositioning Survey for SARS-CoV-2 Antivirals. bioRxiv. 2020 Apr 17. pii: 2020.04.16.044016. doi: 10.1101/2020.04.16.044016. PubMed PMID: 32511357; PubMed Central PMCID: PMC7263415.
3.621
Bohn MK, Lippi G, Horvath AR, Erasmus R, Grimmler M, Gramegna M, Mancini N, Mueller R, Rawlinson WD, Menezes ME, Patru MM, Rota F, Sethi S, Singh K, Yuen KY, Wang CB, Adeli K; IFCC Taskforce on COVID-19. IFCC interim guidelines on rapid point-of-care antigen testing for SARS-CoV-2 detection in asymptomatic and symptomatic individuals. Clin Chem Lab Med. 2021 Apr 27. doi: 10.1515/cclm-2021-0455. [Epub ahead of print] PubMed PMID: 33908222.
3.595
Wong SC, Lam GK, Chen JH, Li X, Ip FT, Yuen LL, Chan VW, AuYeung CH, So SY, Ho PL, Yuen KY, Cheng VC. Air dispersal of multidrug-resistant Acinetobacter baumannii: implication in nosocomial transmission during COVID-19 pandemic. J Hosp Infect. 2021 Aug 14. pii: S0195-6701(21)00288-7. doi: 10.1016/j.jhin.2021.08.005. [Epub ahead of print] PubMed PMID: 34403765.
3.271
Wong SC, Lai-Ha Yuen L, Hon-Kwan Chen J, Yuen KY, Chi-Chung Cheng V. Infection control challenges in handling recurrent blockage of sewage pipes in isolation facility designated for COVID-19 patients. J Hosp Infect. 2021 Mar 7. pii: S0195-6701(21)00086-4. doi: 10.1016/j.jhin.2021.03.002. [Epub ahead of print] PubMed PMID: 33691161.
3.271
Wong SC, Yuen LL, Chan VW, Chen JH, To KK, Yuen KY, Cheng VC. Airborne transmission of SARS-CoV-2: what is the implication of hospital infection control? Infect Control Hosp Epidemiol. 2021 Jul 12:1-10. doi: 10.1017/ice.2021.318. [Epub ahead of print] PubMed PMID: 34250877.
2.938
Wong SC, Leung M, Tong DW, Lee LL, Leung WL, Chan FW, Chen JH, Hung IF, Yuen KY, Yeung DT, Chung KL, Cheng VC. Infection control challenges in setting up community isolation and treatment facilities for patients with coronavirus disease 2019 (COVID-19): implementation of directly-observed environmental disinfection. Infect Control Hosp Epidemiol. 2020 Dec 7:1-29. doi: 10.1017/ice.2020.1355. [Epub ahead of print] PubMed PMID: 33280617.
2.938
Cheng VC, Wong SC, Tong DW, Chuang VW, Chen JH, Lee LL, To KK, Hung IF, Ho PL, Yeung DT, Chung KL, Yuen KY. Multi-pronged infection control strategy to achieve zero nosocomial COVID-19 infection among Hong Kong healthcare workers in the first 300 days of combat. Infect Control Hosp Epidemiol. 2021 Mar 19:1-39. doi: 10.1017/ice.2021.119. [Epub ahead of print] PubMed PMID: 33736729.
2.938
Ng MY, Lee EYP, Yang J, Yang F, Li X, Wang H, Lui MM, Lo CS, Leung B, Khong PL, Hui CK, Yuen KY, Kuo MD. Imaging Profile of the COVID-19 Infection: Radiologic Findings and Literature Review. Radiol Cardiothorac Imaging. 2020 Feb 13;2(1):e200034. doi: 10.1148/ryct.2020200034. eCollection 2020 Feb. PubMed PMID: 33778547; PubMed Central PMCID: PMC7233595.
Chan WM, Ip JD, Chu AW, Tse H, Tam AR, Li X, Kwan MY, Yau YS, Leung WS, Chik TS, To WK, Ng AC, Yip CC, Poon RW, Chan KH, Wong SC, Choi GK, Lung DC, Cheng VC, Hung IF, Yuen KY, To KK. Phylogenomic analysis of COVID-19 summer and winter outbreaks in Hong Kong: An observational study. Lancet Reg Health West Pac. 2021 May;10:100130. doi: 10.1016/j.lanwpc.2021.100130. Epub 2021 Mar 23. PubMed PMID: 33778795; PubMed Central PMCID: PMC7985010.
Chak-Yiu Lee A, Zhang AJ, Fuk-Woo Chan J, Li C, Fan Z, Liu F, Chen Y, Liang R, Sridhar S, Cai JP, Kwok-Man Poon V, Chung-Sing Chan C, Kai-Wang To K, Yuan S, Zhou J, Chu H, Yuen KY. Oral SARS-CoV-2 inoculation establishes subclinical respiratory infection with virus shedding in golden Syrian hamsters. Cell Rep Med. 2020 Sep 22:100121. doi: 10.1016/j.xcrm.2020.100121. [Epub ahead of print] PubMed PMID: 32984855; PubMed Central PMCID: PMC7508015.
Mok BW, Liu H, Deng S, Liu J, Zhang AJ, Lau SY, Liu S, Tam RC, Cremin CJ, Ng TT, Leung JS, Lee LK, Wang P, To KK, Chan JF, Chan KH, Yuen KY, Siu GK, Chen H. Low dose inocula of SARS-CoV-2 Alpha variant transmits more efficiently than earlier variants in hamsters. Commun Biol. 2021 Sep 20;4(1):1102. doi: 10.1038/s42003-021-02640-x. PubMed PMID: 34545191.
Cheng VC, Siu GK, Wong SC, Au AK, Ng CS, Chen H, Li X, Lee LK, Leung JS, Lu KK, Lo HW, Wong EY, Luk S, Lam BH, To WK, Lee RA, Lung DC, Kwan MY, Tse H, Chuang SK, To KK, Yuen KY. Complementation of contact tracing by mass testing for successful containment of beta COVID-19 variant (SARS-CoV-2 VOC B.1.351) epidemic in Hong Kong. Lancet Reg Health West Pac. 2021 Dec;17:100281. doi: 10.1016/j.lanwpc.2021.100281. Epub 2021 Oct 1. PubMed PMID: 34611629; PubMed Central PMCID: PMC8483778.
Chung TW, Zhang H, Wong FK, Sridhar S, Chan KH, Cheng VC, Yuen KY, Hung IF, Mak HK. Neurosensory Rehabilitation and Olfactory Network Recovery in Covid-19-related Olfactory Dysfunction. Brain Sci. 2021 May 23;11(6). pii: 686. doi: 10.3390/brainsci11060686. PubMed PMID: 34071007.

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Address

Biomedical Informatics & Bioinformatics Platform
Institute for Bio-health Research of Murcia (IMIB-Arrixaca)
Carretera Buenavista s/n, 30120
El Palmar, Murcia, Spain

Phones

+34 968885229
+34 968885239
+34 968885249